Coexistence of familial Mediterranean fever and rheumatoid arthritis.

نویسندگان

  • Kiyoshi Migita
  • Seigo Abiru
  • Osamu Sasaki
  • Taiichiro Miyashita
  • Yasumori Izumi
  • Ayako Nishino
  • Yuka Jiuchi
  • Atsushi Kawakami
  • Michio Yasunami
چکیده

Familial Mediterranean fever (FMF) is an autoinflammatory disorder characterized by recurrent febrile polyserositis and arthritis. Although accompanying seronegative spondyloarthropathy has been reported in FMF, coexistence with rheumatoid arthritis (RA) is very rare. This case report describes a Japanese female RA patient who presented with periodic fever. Genetic analysis revealed compound heterozygous mutations in exon 2 and 3 of the MEFV gene (E148Q/G304R/P369S/R408Q). The patient was successfully treated with colchicine with 3-year follow-up.

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Rheumatoid Arthritis and Familial Mediterranean Fever or Sacroiliitis Accompanied by FMF

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عنوان ژورنال:
  • Modern rheumatology

دوره 24 1  شماره 

صفحات  -

تاریخ انتشار 2014